Andrew Weitz of William Morris Endeavor Entertainment confirmed the rapper's death in an email Tuesday, without giving a cause of death or saying where he died.
Dwight Arrington Myers, the rapper known as Heavy D of Heavy D and the Boyz, and his crew released their debut album "Living Large" in 1987. Their hits included "Now That We Found Love" and "Who's the Man."
In the mid-1990s, Heavy D became president of Uptown Records, the label that released most of his albums and was also the home to acts like Mary J. Blige and Jodeci.
He released a new album, "Love Opus," in September.