The accident happened Saturday afternoon on Crosby-Dayton near Adlong School Rd.
According to investigators at the scene, it appears the woman lost control of her car and ran off the roadway. The vehicle hit a sign and ran into a tree.
Officials said the car and the grass around it caught on fire immediately.
The woman died inside the car.
No other details were released. Stay with Eyewitness News and abc13.com for more information as it becomes available.