It happened on the Gulf Freeway near FM 517 last night.
Dickinson police say the driver of a pickup truck was driving recklessly when he lost control and struck the outside retaining wall.
A motorcycle with another passenger crashed into the truck.
The victims were transported to an area hospital, where the infant died.
The truck driver and the infant had to be transported by ambulance after a Life Flight helicopter experienced mechanical difficulties.
Police say the accident was not alcohol- or drug-related
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