"It was immediately apparent to officers responding on the scene that LaBeouf was intoxicated and he was subsequently placed under arrest," Wolf said.
Wolf said LaBeouf was booked then released for misdemeanor DUI. The 22-year-old actor was taken to Cedars-Sinai Medical Center and was being treated for injuries to his left hand and a knee, as well as a minor head injury, Wolf said.
A woman passenger in LaBeouf's truck and the driver of the other vehicle were not seriously injured. Wolf did not know the identities of the woman or the other driver.
The cause of the crash remained under investigation, Wolf said. Two attorneys listed for LaBeouf did not immediately return calls from The Associated Press on Sunday.
Melissa Kates, a publicist for the actor, said LaBeouf underwent hand surgery and plans to return to work within a month. She declined further comment.
The accident occurred when LaBeouf, who was headed northbound on La Brea Avenue, tried to turn onto Fountain Avenue, Wolf said. The intersection is the location of "High Voltage," the tattoo parlor where the TLC reality show "LA Ink" is filmed.
LaBeouf starred in last year's summer smash hit "Transformers," and this year appears opposite Harrison Ford in "Indiana Jones and the Kingdom of the Crystal Skull."
LaBeouf has had previous brushes with the law, but until now they'd been relatively harmless — to the degree that they only served to reinforce his image as a Hollywood good guy with an edge.
A drunken confrontation with guards at a Walgreens in Chicago late last year led to misdemeanor criminal trespassing charges. Arresting police in that incident noted that LaBeouf was "very courteous and polite," and the charge was dropped because the drug store didn't want to pursue the matter.
In a lighthearted retelling of the incident to David Letterman on the "Late Show," LaBeouf said: "Drinking and driving is one thing, but drinking and shopping ... it's just as bad."
LaBeouf was separately cited in February for smoking where he shouldn't in Burbank, but a judge later dismissed the charge.
Slideshow archive | Local events | Contests | Headlines at a glance