Sajoyia Griffin scored 11 points to lead Wagner (36-2), which advanced to the state tournament in just its second year of varsity competition.
Senior Nneka Ogwumike is the McDonald's All-American who has signed with Stanford, but it was her younger sister who had the big first half as Cypress Fairbanks built a big lead. Chiney Ogwumike scored 12 points and grabbed eight rebounds as the Bobcats built a 42-21 lead by halftime.
Wagner was overwhelmed from the start. With the Ogwumike sisters -- who both stand 6-foot-2 -- gobbling up rebounds and stretching to alter shots and shut down passing lanes, Wagner committed 10 turnovers in the first quarter.
Wagner tried to counter with its own size in the middle but 6-foot-3 Amber Roberson and 6-foot-2 BreAnna Brock were no match against the stronger, sharper Ogwumike sisters, who also had four assists.
Rhian Rogan and Mansa El hit 3-pointers as Cypress Fairbanks built a 17-point lead by the end of the first. In the second, Nneka Ogwumike stepped out to the top of the arc and swished a long 3-pointer.