At about 1:29 a.m., officers responded to a shooting on the Katy Freeway near Highway 6 at a LaQuinta Inn.
Upon arrival, officers found a 31-year-old woman suffering from a gunshot wound to her head in the passenger seat of a car. She was taken to Ben Taub Hospital in critical condition.
Investigators said the woman was with a man who was in the driver's seat. She was then shot after motioning toward someone, who police believed was involved, walking outside the vehicle for a cigarette.
Witnesses told police they saw at least one man running from the area. HPD said they are looking into surveillance video footage, but do not have a description of the suspect.