Officers said the woman was shot while riding in a car at about 7:40 p.m. Monday in the 8100 block of Gulf Freeway.
A black SUV with out-of-state plates pulled up and someone started firing. Police said the possible suspect may be a young Black man.
The woman is believed to have been in her 30s. Police said she was in the car with her boyfriend and two children, one of which is a teenager and the other is about a year old.
Police have not determined if there was a motive.