Investigators said the fire department responded to a fire at the 4200 block of S. Kirkwood around 11 p.m. Tuesday and found the 40-year-old victim with severe burn injuries.
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She told firefighters that she was sleeping when someone set her on fire.
A witness dragged her away and extinguished the flames.
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She was taken to Memorial Hermann Medical Center and is in critical condition.
Meanwhile, Eyewitness News has obtained surveillance video showing the moments before the woman was set on fire.
The Houston Police Department is urging people to come forward with any information about this case. Call 713-308-8800 or Crime Stoppers at 713-222-TIPS.