Investigators say a man driving an SUV was traveling eastbound on Fuqua when he crossed over a grassy median and crashed into the pregnant woman's vehicle.
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The woman was eight months pregnant. She was rushed to the hospital in critical condition.
After an emergency c-section, the baby passed away on Monday.
The man who caused the crash left the scene and is still on the run, police say.
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"We need to find the person. There was a living person inside of her and he did wrong," said Erika Martinez, a neighbor.
Authorities are asking anyone with information about the man involved in the crash to call the Houston Police Department.
Pregnant woman loses child during Houston hit-and-run crash
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