Susan Edmondson was last seen at 9:30 a.m. in the 11700 block of River Vine Court in Tomball.
She was driving a gray 2013 Honda CRV with Texas license plate CDK3698.
Authorities say she has been diagnosed with a cognitive impairment.
She is 5'7", 135 pounds with brown hair and brown eyes.
She may have been wearing a white or pink shirt and khaki capris.
Officials believe Edmondson's disappearance poses a credible threat to her own health and safety.
If you have any information, you're urged to contact Precinct 4 at 281-376-3472.