A man left after what deputies called a disturbance on Lake Robbins Drive at about 9 p.m.
Deputies said they tried to stop him, but the suspect lost control of the vehicle and crashed on an embankment of the Woodlands Parkway Bridge.
The driver, who was not wearing a seatbelt, was ejected from the vehicle and died. Deputies said he was the only person in the vehicle.
The suspect's identity has not yet been released.