Tajauna Thomas, 38, and Richard Mouton, 34, were arrested after allegedly breaking into a home in the 4000 block of Lockwood near Calvacade at about 1:30 a.m. on Monday, Jan. 26.
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Police said both masked suspects and the 72-year-old woman exchanged gunfire before HPD was dispatched to the scene.
HPD said officers arrived and found Thomas, Mouton, and the woman injured. Paramedics with the Houston Fire Department confirmed the 72-year-old died at the scene.
Officials said Mouton is still in the hospital and has not been charged as of Tuesday afternoon.
It is unclear if the woman was the suspects' target or if there was a motive. Officials confirmed that other people were inside the home at the time, but police did not elaborate.
Anyone with information in this case is urged to contact the HPD Homicide Division at 713-308-3600 or Crime Stoppers at 713-222-TIPS( 8477).