Officials said it happened in the hotel's lobby on Aug.1, just before 6 a.m. in the 5300 block of Westheimer.
Police said the two suspects entered the lobby and went to the elevators, where they located the victim.
Officials said that the victim had just returned to the hotel after winning a large sum of money at a private social club in the 6100 block of Westheimer.
The man was forced to the ground by the suspects with an unknown object before they made away with his belongings.
Surveillance video from the hotel lobby showed the suspects running from the lobby and into a waiting white four-door sedan that sped off.
Anyone with information is urged to contact Crime Stoppers of Houston directly by calling 713-222-TIPS (8477) or submitting an online tip on the Crime Stoppers website or the app.