Jeramie Doucet, 32, was already charged with two counts of intoxication assault following the multi-vehicle crash.
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The Harris County Sheriff's Office says Doucet will now face charges of intoxication manslaughter and failure to stop and render aid.
According to authorities, Doucet was speeding southbound on Highway 6 when he crashed into other vehicles stopped at a red light around 9:30 a.m. Saturday.
"As he was approaching the intersection, he (Doucet) ran into the back of a Ford Expedition with two females, which had stopped for the heavy traffic at the intersection." Deputy Thomas Gilliland said in a press release. "The Expedition also struck other vehicles that started a chain reaction."
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Doucet allegedly made an attempt to flee the scene but was detained at Texas Roadhouse and taken to a hospital.
Authorities say Doucet admitted to taking PCP, but declined to answer questions.
At least four people were hospitalized, including the 37-year-old woman who died, and a second woman who is still in critical condition.
Doucet is currently being held on a $5,000 bond.