HPD says officers were responding to a disturbance call at 10:40 p.m. Saturday in the 3800 block of Hickok Lane when they heard multiple gunshots.
"Once officers arrived, they were met with a large crowd...they also found a female with a gunshot wound to the leg area and a male with a gunshot wound to the stomach area," Lt. Ali with HPD said.
HPD says the boy died at the hospital, and the 15-year-old girl is expected to survive.
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Police say the male in the photo may have information about the shooting.
Investigators are asking anyone with information to contact HPD's Homicide Division or Crime Stoppers of Houston at (713) 521-4600.