The Houston Police Department posted an update on social media about a shooting that occurred at about 1:25 p.m. at 4001 Corder St. near Scott Street.
HPD said the 16-year-old boy was fatally shot while a second person, a 19-year-old man, was wounded and rushed to a hospital.
Police added that the suspects took off in a vehicle before officers arrived. A female, whose age police didn't disclose, was detained, but investigators didn't clarify her role in the case.
Police earlier told ABC13 that a 911 caller reported hearing several gunshots.
SkyEye flew over the active scene, where crime scene tape surrounded a parking lot area.