According to the Houston Police Department, the deadly crash happened at about 12:50 a.m. at 63 East Crosstimbers Street.
HPD said a pedestrian was lying down in a moving lane of traffic when someone in a gray Nissan Versa hit him.
Paramedics arrived at the scene and pronounced the pedestrian dead, police said.
The 61-year-old driver, who police say did not show any signs of intoxication, was questioned and released.
Witnesses told investigators the pedestrian was acting erratically before lying on the roadway.
The victim's identity is pending verification by the medical examiner's office.