Officials said that numerous neighboring fire departments have been called to help with what they describe as "a very volatile situation."
The Montgomery County Office of Homeland Security and Emergency Management has confirmed that they are also on the scene to provide medical assistance.
It is unclear what caused the explosion at this time.
Traffic on US-59 is being rerouted to FM 2665, according to officials.
Authorities are urging people nearby to avoid the area and stay inside until the fire is under control.