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The Harris County Sheriff's Office tells Eyewitness News the driver of a black Harley-Davidson was going southbound on the service road around 3:30 a.m. Thursday.
Officials believe he was trying to enter the mainlanes of the freeway, lost control, hit a guardrail and flew off the bike.
He was wearing a helmet, however authorities say it was thin and would not have prevented his death.
Another vehicle was trying to get on the freeway at the same time and hit the motorcycle.
A second vehicle in a dark-colored SUV hit the motorcycle and the man.
None of the drivers stopped.
The sheriff's office says the only description they have is of the SUV. They believe it's a newer model black GMC Terrain or a similar vehicle with damage.
A witness says the man was still alive before being hit by the SUV.
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The mainlanes of the freeway and the feeder road are open.
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