According to Houston police, homicide detectives were called to the 5700 block of the freeway after a person was found shot to death at about 11:10 a.m. Monday.
A caller first alerted authorities to the shooting, police said.
One person was detained at the scene.
TranStar cameras showed a heavy law enforcement presence as well as EMS.
The toll lanes reopened just after 4 p.m.