Houston TranStar first reported the crash just after 5 a.m. in the northbound lanes before FM-525/Aldine Bender Road.
The crash cleared nearly five hours later, at about 9:48 a.m. All northbound lanes have reopened.
SkyEye flew over the scene, where a white sedan appeared to be T-boned by a large truck. Authorities confirmed that at least one person died in the crash.
Drivers were directed to take Homestead or the Hardy Toll Road as an alternate route.
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