The Houston Fire Department said crews were dispatched just before 3 p.m. at the De Priest and Fortune intersection.
SkyEye flew over the house, where firefighters were still putting out hotspots. HFD said the fire was out by around 3:15 p.m.
As of 3:24 p.m., fire officials said crews were not able to complete a full search of the home due to the possibility of a collapse.
No injuries have been reported.
Investigators are still working to determine the cause of the fire.