According to neighbors, the fire started around 4:30 a.m. near Sharondale and Bellfort.
Video shared with ABC13 shows multiple fire crews responding to the scene as flames and smoke emanated from a home's roof.
One neighbor said they feared the fire was going to spread to their home, too.
ABC13 crews reported that one home appeared to be a total loss, while another home and a car were damaged.
ABC13 has reached out to the Houston Fire Department to learn whether anyone was injured.
This is a developing story. Eyewitness News is continuing to gather facts.
Watch live breaking news coverage from ABC13 on our 24/7 streaming news channel.