Houston TranStar reported the Brazoria County crash at 5:47 p.m., describing it as an accident involving two vehicles.
SkyEye13 flew over the scene on Tuesday afternoon, showing officials diverting all northbound traffic to exit the highway as crews responded to the incident.
This is a developing story. Eyewitness News is continuing to gather facts.
Traffic tie-ups are slowing drivers around the Houston area.
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