Houston police originally said someone assaulted a man in a wheelchair at about 8:40 a.m. in the 2200 block of Southmore Boulevard, just off SH-288.
The man, who police believe was homeless, was taken to an area hospital, where he died from his injuries, HPD said.
In a later update, HPD said it appeared the victim fell out of his wheelchair while arguing with another homeless man. Investigators believe his death may have been medical-related.
Police said the incident was caught on video, and it doesn't appear that either man assaulted the other.