Deputies say he crashed after he gave the finger to a woman he was passing.
A woman told authorities she was driving north on Eldridge when the motorcyclist passed her Suburban on the right and gave her the finger. He then turned around and did it a second time, but lost control and crashed.
"After he gave her the finger a second time, he lost control, hit the curb and struck his head. He was unconscious at the scene," said Harris County Sheriff's Sgt. Dashana Cheek-McNeal.
The motorcyclist was taken by Life Flight to Memorial Hermann Hospital.
Deputies say the other driver did not strike him.