Robert Watkins, 73, left on foot from the 8600 block of Westcott, according to authorities.
Watkins, also known as Earl, is described as an African-American man, 5 feet and 9 inches tall, 160 pounds, with grayish hair and brown eyes.
The 73-year-old was last seen wearing jeans with black patches, a blue jacket, and a yellow hat.
If you see Watkins, call the Houston Police Department Missing Persons Unit at 832-394-1840.