Harris County Sheriff's investigators said it started with a fight around 9:30 p.m. on the 12000 block of Wild Pine between the man and his wife, and when the woman left the room to bring her 1-year-old daughter upstairs, her 15-year-old son showed up with several other teenagers.
A shot was fired and the teens, including the victim's stepson, left the house.
Deputies said it is unclear who shot the man and who brought the gun.
No arrests have been made.