It happened at 410 North Sam Houston Parkway East near Imperial Valley Drive. Investigators at the scene told Eyewitness News it started as a disturbance at a nearby parking lot.
Several people began shooting at the car. The man was shot multiple times and died at the hospital, police say.
A description of the suspect or suspects was not immediately released.
According to a map of the area, there are several businesses nearby.
This is a developing story. Check back for updates.