Several lanes were closed on US-59 northbound at West Airport Boulevard after a crash was reported at about 4:19 p.m. Stafford police said three vehicles, including the big rig, were involved.
It's not immediately known what caused the crash.
At one point, the entire freeway was shut down. All of the northbound lanes reopened just after 8 p.m.
Northbound lanes were at a standstill all the way to Sugar Land. Southbound lanes were also slow on US-59 due to onlookers, according to Don Armstrong in SkyEye.
SkyEye captured the 18-wheeler spilling diesel. Hazmat units were called to the scene.
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