DPS said the crash happened at Calvary Road on Saturday afternoon.
According to DPS, two 3-year-olds and a 50-year-old woman were also transported to hospitals.
She, along with the 3-year-olds were believed to be in the same vehicle.
I-45 north remained closed for several hours.
The cause of the crash is unknown. No injuries to those in the other vehicle have been reported.
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