Investigators say Rebecca Suhrheinrich, 58, has not been seen since Friday, when she didn't show up at her job.
On Monday, colleagues grew more concerned when she missed a second day of work.
Coworkers who arrived at her apartment at 200 Dominion Park were let in by a maintenance man, and that is when they found what appeared to be signs of a struggle.
The Houston Police Department says that Rebecca's car was missing, but it was later found at a nearby apartment complex.
Investigators say her apartment was ransacked, with belongings thrown everywhere.
Police are now considering this a homicide case, although her whereabouts are still unknown.
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