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The crash happened at about 2:30 a.m.
ABC13 is working to get more information about the crash, including confirmation from authorities on whether two people were killed.
Authorities say they believe a sedan driving the wrong way crashed head on with an 18-wheeler hauling materials for USPS.
ABC13 is told that the driver of the 18-wheeler was transported to the hospital.
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Our crew at the scene saw the front of the big rig hanging halfway off the road.
At one point, the northbound and southbound lanes were shut down but have since reopened.
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