It happened around 4 a.m. near Bayway and Thompson Road.
Three vehicles were involved in the crash, including a driver going the wrong way in the eastbound lanes, police said. The wrong-way driver crashed into an 18-wheeler and a pickup truck.
The driver of the pickup truck was treated for minor injures. The eastbound lanes were reopened after several hours.
HOUSTON TRAFFIC
Get real-time traffic data from Houston's roads and avoid traffic slow-downs.
Want to be the first to know about traffic trouble on the road? Sign up for our traffic alerts sent straight to your phone through our ABC13 app. Manage your notifications from the settings tab.
On mobile, use two fingers to zoom in to specific roads.
Live traffic map
Do you hate Houston traffic as much as we do? Join the club!