It happened around 7 a.m. on FM 723 at Huntington Lane north of Rosenberg.
While it wasn't clear what exactly led to the crash, at least two vehicles and a Lamar Consolidated ISD school bus were involved.
The bus was rear-ended by a pickup, according to the Fort Bend County Sheriff's Office. Nobody on the bus was injured, but one person was taken away in an ambulance with what were described as non-life threatening injuries.
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