Houston police said the shooting happened at 17030 Imperial Valley Drive on July 13.
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Alberto Ayala Guerrero, 55, was charged with murder after police say he assaulted and shot his wife, 32-year-old Yenisleydi Dominguez, to death during an argument with her and her brother.
Police say Guerrero fled the scene on foot and was believed to possibly be driving a white Kenworth dump truck with no license plates.
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According to authorities, an investigation determined that Guerrero fled to Ontario, Canada, in a Honda Civic. While there, police say Guerrero was involved in a pursuit with officers. According to the Canadian Special Investigations Unit, Guerrero jumped off an overpass during the chase and onto moving traffic.
Police say he was taken to a hospital, where he was pronounced dead.