The Houston Police Department responded to the shooting at about 7:30 p.m. on Tall Willow Drive in the Greater Inwood neighborhood.
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The victim's parents told police they heard some kind of argument outside and then at least one gunshot. That's when they went outside and found their adult son had been shot.
First responders tried to help the man, but he was pronounced dead at the scene.
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HPD said the suspect fled the scene. There is no word yet on the motive of the shooting.
Investigators are talking to witnesses and looking for surveillance video to gather more information.