Houston Police Department officers responded to the 10600 block of Martin Luther King Boulevard near Airport Boulevard in the early hours of Thanksgiving Day.
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According to police, an eyewitness saw the driver going fast and running a red light.
It appears the car struck a curb, left the roadway, and hit a tree. The driver died at the scene.
Two of her passengers are now in the hospital. Police say one has more substantial injuries than the other. A third passenger reportedly had minimal injuries.
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HPD said responders had to cut out part of the vehicle to extricate a passenger due to the impact of the tree.
As of right now, police do not have evidence of alcohol, and no charges are expected since the driver died.