Pittsburgh will receive pitcher Joe Musgrove, third baseman Colin Moran, reliever Michael Feliz and Minor League outfielder Jason Martin from the Astros.
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Learn more about new Houston Astros pitcher Gerrit Cole
Cole went 12-12 with a 4.26 ERA and 196-to-55 strikeout-to-walk ratio while making a career-high 33 starts in 2017.
He has one year of arbitration remaining and could command a hefty salary bump in 2019, one of the reasons the Pirates had explored trading him in recent weeks.
Cole will be added to a rotation that features Justin Verlander, Dallas Keuchel, Charlie Morton, Lance McCullers Jr. and Brad Peacock.
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The Astros will open the 2018 season against the Texas Rangers on March 29.
Information from ESPN was used in this report.
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