Firefighters were called to a one-story home on Randall Street at Texas Avenue at 3:15 a.m.
When they arrived, they found heavy flames and smoke pouring from the home.
EYEWITNESS VIDEO: Massive 2-alarm fire engulfs Pasadena home
Eyewitness video of Pasadena fire
A woman was found running up and down the street, screaming for help. She said a man was trapped inside the home and needed help.
Hector Garcia, 41, was pulled from the home as crews made their way into the inferno.
He was placed in an ambulance and rushed to Bayshore Medical Center, but his family said he has died from his injuries.
His parents said they were able to escape, but sadly, Garcia could not be rescued by his family members.
There is major damage to the home after the fire broke out inside a back bedroom, according to firefighters.
Rescuers do not know how the fire started, and are investigating the cause of the blaze.
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