The Hitchcock Police Department said officers received multiple reports of gunshots at about 8:30 p.m. in the area of Wayne Johnson Avenue and Prino Road, which is just off Highway 6.
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According to police, officers arrived to find a Black woman with wounds still breathing. The woman was rushed to UTMB Galveston where she died.
The police department also found a child inside the vehicle unharmed.
Since the shooting, police reached out to Galveston County Sheriff Henry Trochesset for help in the investigation.
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As of mid-morning Friday, authorities do not have anyone in custody and they could not disclose any other information, including a description of the shooter and a motive.
Family and a close family friend identified the 27-year-old mother as Bria Lockett, who lived in Texas City. According to the family, Lockett called 911, but by the time the family arrived to the local hospital, Lockett had passed away. The father of her 3-year-old boy lives in Hitchcock, family said.
Georgia Huff, who was born and raised in Hitchcock, said one of her grandchildren is related to Lockett. Huff said she heard multiple gunshots Thursday night and was shocked to hear what happened when her family called early Friday morning.
"She wasn't nothing but an innocent bystander sitting in that car," said Huff.
Both family and neighbors tell ABC13 that Lockett was not the intended target and they are urging those responsible to turn themselves into authorities.
"Turn yourself in," said Wilbert Lee, a neighbor who heard the gunshots Thursday night, "because like I say it doesn't have to come to that."
Anyone with any information is ask to call the Galveston County Sheriff's Office.
ABC13's Roxie Bustamante is looking into the investigation into the deadly mystery in Galveston County. Get updates by following her on Facebook, Twitter and Instagram.