The department reported that the boy -- who is between the ages of 6 and 10 -- died in early February. The boy had pre-existing health conditions that contributed to his death, officials said.
With flu activity remaining high, health officials encourage people six months and older to get vaccinated.
On Tuesday, officials confirmed Harris County's first flu-related death of a child. A 10-year-old girl with underlying health conditions died this month, according to the Texas Department of State Health Services.
The flu season lasts through May.
RELATED: 10-year-old girl is first flu-related child death in Harris County
Harris County confirms first child flu death