The terms of the transaction were not disclosed.
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Favor will continue to operate independently as a separate brand, H-E-B said. All of Favor's employees and runners will be retained.
"I am thrilled to have H-E-B join forces with another well respected and innovative Texas company," H-E-B's Chief Operating Officer Martin Otto said in a press release.
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Founded in 2013, Favor has quickly expanded its presence to 50 cities across the state of Texas.