The Harris County Sheriff's Office said deputies also took a suspect, blamed for causing the crash and still alive, into custody.
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Crews responded to the frontage road intersection of the Grand Parkway and Highway 249 for the reported crash.
HCSO told ABC13 that a pursuit began on the parkway at US 290. Deputies added they were pursuing a pickup hauling a motorcycle in its bed that were both reported stolen out of San Antonio.
Speeds reached 115 mph at several points of the pursuit, which nearly resulted in a crash before ending at Highway 249, the sheriff's office said.
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The suspect and victim's identities have not been released.
SkyEye observed what appeared to be the suspect being loaded on an ambulance. That person is expected to face several charges from the incident.