The crash was reported around 4:51 a.m. in the inbound lanes of I-10 East at Normandy.
Investigators say a red car was stalled on the freeway when the driver got out of the car and was hit by a white pickup truck.
The driver of the red car died on the scene.
An 18-wheeler driving down the freeway attempted to avoid the crash, but overturned.
More than five hours after the accident, two lanes are open on the inbound lanes of -10 East at Normandy.
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