Video captured at the scene by SkyEye showed the three inbound left lanes on US-290 were blocked, but by 6:50a.m., the crash was reported cleared.
Backups go for at least four miles, officials said.
Drivers coming in from Jersey Village or Cypress are impacted and urged to take Eldridge Parkway to Little York as an alternate route.
Injuries are reported at the scene but it is unclear the extent of those injuries.
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