Police told ABC13 that the crash happened just before 3 a.m. on the 3700 block of Parker Road, and that it appeared to be a single-vehicle accident.
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The man driving suffered a heart attack prior to the crash, according to his stepson. The front seat passenger tried to correct the wheel, police said.
The car went into the ditch, hit a large tire and flipped several times.
SURVEILLANCE VIDEO OF CRASH
Surveillance video of fatal crash on Parker Road
The driver and a woman in the back seat died. The front seat passenger survived and was taken to a hospital.
A neighbor told Eyewitness News Reporter Charly Edsitty that he heard a loud noise just outside his home after the crash.
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"Scared me to death. I ran out here. There were people inside the car yelling 'Help me! Help me!'"
Investigators said that speed may have also been a factor.