The Houston Police Department said the shooting happened at about 8:30 p.m. in the 8500 block of Martin Luther King Boulevard.
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Investigators said an armed suspect in a white Camaro fired several rounds at an SUV with a family inside.
The SUV driver, a 28-year-old man, was shot in his left leg, prompting him to continue driving southbound before making a sudden westbound turn onto Reed Road.
The man crashed into a ditch at Construction zone, according to police.
HPD said the man's sons, who are 4 and 9 years old, and their mother were unharmed.
The wounded father was taken to the hospital and is expected to be OK.
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"Thank God the kids were not injured," Lt. Ignacio Izaguirre said. "At this point, we're going to have to do a follow-up investigation."
Investigators said the victim does not recognize or know the suspect.
Izaguirre said there wasn't an argument on the road that might have led to the shooting.
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