Harris County sheriff's deputies responded to shots fired on the feeder road in the 16900 block of the I-10 East Freeway at about 12:30 a.m. Thursday.
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That's where deputies found a man in his 30s with multiple gunshot wounds. Paramedics pronounced him dead at the scene.
In an update, deputies said the suspect they're looking for is a Black man in his early 20s who was wearing a white hoodie and dark-colored pants during the shooting. Witnesses reportedly told deputies they saw the suspect run off after they heard gunshots.
Investigators said the victim and shooter may have known each other. Deputies believe they had some sort of altercation outside of the motel before shots were fired.
"At this point, we're just going to be canvassing for witnesses, surveillance video, and following up on additional leads that might come in," Sgt. Sidney Miller said.
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Deputies believe the shooter could live in one of the motels near the shooting scene.
An employee at the motel told ABC13 the business has surveillance cameras, but they don't point in the direction of the shooting.
If you know anything about what happened, you're encouraged to call Crime Stoppers at 713-222-TIPS or the Harris County Sheriff's Office Homicide Unit at 713-274-9100.
For news updates, follow Chaz Miller on Facebook, Twitter and Instagram.