Deputies with the Harris County Sheriff's Office said the crash happened at about 2:30 a.m. on Westheimer Road near Addicks Clodine Road.
The victim, who was driving a white Mercedes, lost control before hitting a pillar, HCSO said.
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Man dies after grabbing onto vehicle and falling off in Acres Homes
Officials said that's when the car burst into flames with the driver inside.
According to deputies, no one else was inside that vehicle.